Products
Our custom molecular serotyping microarrays were developed as a genomics-based tool to dissect the pathogens present in complex clinical samples. A key advantage of this technology was the sensitive detection of multiple serotype carriage and estimating the relative abundance of each serotype. A number of simultaneous analyses have been incorporated in the designs available for each pathogen:
ArraySero: molecular serotyping by combination of cps genes detected in sample
AbR: presence of gene-mediated antimicrobial resistance markers or key SNPs
PathID: detection of co-colonisers or discrimination of closely related species
ArrayCGH: genotyping based on genome backbone to determine genomic lineage
Senti-SP
Streptococcus pneumoniae: 100 serotypes; asymptomatic nasopharyngeal carriage; pneumococcal disease; pneumonia, meningitis, septicaemia; polysaccharide conjugate vaccines
Senti-GBS
Streptococcus agalactiae: Group B Strep (GBS); 10 serotypes; asymptomatic rectovaginal carriage; maternal transmission to newborns; sepsis, pneumonia, meningitis; polysaccharide conjugate vaccines
Senti-HI
Haemophilus influenzae: 6 serotypes; NTHi non-encapsulated; asymptomatic nasopharyngeal carriage; Hib disease; pneumonia, meningitis, septicaemia; polysaccharide conjugate vaccines
Senti-NM
Neisseria meningitidis: 12 serogroups; asymptomatic nasopharyngeal carriage; meningococcal disease; meningitis, septicaemia; polysaccharide conjugate vaccines; protein vaccines
